Opportunity Information: Apply for PA 20 204
The Mentored Patient-Oriented Research Career Development Award (K23) is an NIH career development grant designed to help early-career clinician-researchers build the skills, experience, and publication track record needed to become independent investigators in patient-oriented research. It is specifically aimed at individuals who already hold a clinical doctoral degree and have made a clear commitment to conducting research that directly involves human participants. In this particular parent announcement, the focus includes independent basic experimental studies with humans, meaning the proposed work should involve prospective or direct interaction with people (or their identifiable data or specimens in ways that meet NIH definitions of human subjects research) and should be structured as a mentored career development experience rather than a standalone research project. The core idea is that NIH funds protected time, structured training, and supervised research so the candidate can transition from mentored work into an independent research career.
This opportunity is issued by the National Institutes of Health as a discretionary grant under Funding Opportunity Number PA-20-204. The funding activity category is listed broadly across areas such as education, environment, health, and social services, reflecting NIH's wide mission and the fact that multiple NIH Institutes and Centers may participate depending on the scientific topic. The opportunity is associated with multiple CFDA numbers (including 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.361, 93.853, 93.865, 93.866, and 93.867), which typically correspond to different NIH Institutes and Centers that may support K23 applications aligned with their program priorities.
Eligibility is broad at the organizational level, covering many types of U.S.-based applicants that can administer NIH grants. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; and Native American tribal organizations other than federally recognized tribal governments. The announcement also allows nonprofit organizations, whether they have 501(c)(3) status or not (as long as they are not institutions of higher education for those categories), and it permits for-profit organizations (other than small businesses) as well as small businesses. In addition, NIH explicitly highlights a range of institution types and community-centered organizations as "other eligible applicants," including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible agencies of the federal government, and U.S. territories or possessions.
At the same time, the announcement draws clear boundaries around foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations) and non-domestic (non-U.S.) foreign institutions are not eligible to apply as the applicant organization. Non-domestic components of U.S. organizations are also not eligible to apply. However, "foreign components" are allowed when they meet NIH's definition in the NIH Grants Policy Statement, which typically means that part of the project may involve a significant element being conducted outside the U.S. under the U.S. applicant's award, subject to NIH review and approval. Practically, this setup is meant to keep the award anchored at an eligible U.S. organization while still permitting specific international elements when scientifically justified.
The original closing date listed for this opportunity is May 7, 2024, and the opportunity was created on May 11, 2020. The source information provided does not list an award ceiling or an expected number of awards, which often means applicants need to rely on NIH institute-specific guidance, K23 policy limits, and the budget and effort rules in the full funding opportunity announcement and related NIH policy documents. Overall, this K23 parent announcement is best understood as a mentored career development pathway for clinically trained investigators whose research requires direct involvement of human participants and who need dedicated time and mentorship to develop into independent patient-oriented researchers.Apply for PA 20 204
- The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Basic Experimental Studies with Humans Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.361, 93.853, 93.865, 93.866, 93.867.
- This funding opportunity was created on 2020-05-11.
- Applicants must submit their applications by 2024-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: NIH Mentored Patient-Oriented Research Career Development Award (K23) - PA-20-204
What is the Mentored Patient-Oriented Research Career Development Award (K23)?
The K23 is an NIH career development grant designed to support early-career clinician-researchers as they build the skills, research experience, mentorship, and publication record needed to become independent investigators in patient-oriented research.
What is the Funding Opportunity Number (FON) for this K23 announcement?
The Funding Opportunity Number listed for this opportunity is PA-20-204.
Who issues this grant opportunity?
This opportunity is issued by the National Institutes of Health (NIH) as a discretionary grant program.
What is the main purpose of this K23 parent announcement?
The core purpose is to fund protected time, structured training, and supervised (mentored) research so that a clinician-researcher can transition from mentored work into an independent research career focused on patient-oriented research.
Who is this award intended for?
It is specifically aimed at early-career clinician-researchers who already hold a clinical doctoral degree and have made a clear commitment to conducting research that directly involves human participants.
What kind of research is emphasized in this particular K23 parent announcement?
The focus includes independent basic experimental studies with humans. In practical terms, the proposed work should involve prospective or direct interaction with people, or involve identifiable data or specimens in ways that meet NIH definitions of human subjects research.
Does the proposed work need to involve human participants?
Yes. The description emphasizes research that directly involves human participants or uses identifiable human data/specimens in a way that meets NIH human subjects research definitions.
Is this award meant to fund a standalone research project?
No. The opportunity is framed as a mentored career development experience. The research is part of a structured, supervised development plan rather than a standalone research project.
What does NIH typically support through this K23 award?
NIH supports protected time, structured training, and supervised research activities intended to help the candidate develop into an independent patient-oriented researcher.
What is the funding activity category for this opportunity?
The funding activity category is listed broadly across areas such as education, environment, health, and social services, reflecting NIH's broad mission and multi-institute participation depending on the topic.
Do multiple NIH Institutes and Centers participate in this K23 opportunity?
Yes. The information indicates that multiple NIH Institutes and Centers may participate, depending on the scientific topic and alignment with their program priorities.
What CFDA numbers are associated with this opportunity?
The opportunity is associated with multiple CFDA numbers, including 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.361, 93.853, 93.865, 93.866, and 93.867.
What kinds of organizations are eligible to apply?
Eligibility is broad for U.S.-based applicant organizations that can administer NIH grants. Eligible applicants include various levels of government (state, county, city/township), special district governments, independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, public housing authorities and Indian housing authorities, and Native American tribal organizations other than federally recognized tribal governments.
Are nonprofit organizations eligible to apply?
Yes. The announcement allows nonprofit organizations, whether or not they have 501(c)(3) status (as long as they are not institutions of higher education for those nonprofit categories).
Are for-profit organizations eligible to apply?
Yes. For-profit organizations (other than small businesses) are permitted, and small businesses are also permitted.
Are minority-serving institutions and community-based organizations included as eligible applicants?
Yes. NIH explicitly highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving Institutions, HBCUs, TCCUs, and also faith-based or community-based organizations and regional organizations.
Are U.S. territories or possessions eligible to apply?
Yes. The announcement lists U.S. territories or possessions among the "other eligible applicants."
Can an eligible agency of the federal government apply?
Yes. Eligible agencies of the federal government are listed among the "other eligible applicants."
Are foreign (non-U.S.) organizations eligible to apply as the applicant?
No. Non-domestic (non-U.S.) entities (foreign organizations) and non-domestic foreign institutions are not eligible to apply as the applicant organization.
Can a non-domestic component of a U.S. organization apply?
No. Non-domestic components of U.S. organizations are also not eligible to apply.
Are foreign components allowed under this opportunity?
Yes. "Foreign components" are allowed when they meet NIH's definition in the NIH Grants Policy Statement. This generally means a significant element of the project may be conducted outside the U.S. under the U.S. applicant's award, subject to NIH review and approval.
What is the practical intent behind allowing foreign components but not foreign applicants?
The intent is to keep the award anchored at an eligible U.S. organization while allowing specific international elements when scientifically justified and approved by NIH.
What was the original closing date listed for this opportunity?
The original closing date listed is May 7, 2024.
When was this opportunity created?
The opportunity was created on May 11, 2020.
Is an award ceiling listed in the provided information?
No. The source information provided does not list an award ceiling.
Is the expected number of awards listed in the provided information?
No. The source information provided does not list an expected number of awards.
If the award ceiling and number of awards are not listed, what does that imply for applicants?
It suggests applicants may need to rely on NIH institute-specific guidance, K23 policy limits, and the budget and effort rules described in the full funding opportunity announcement and related NIH policy documents.
How should this K23 parent announcement be understood overall?
It is best understood as a mentored career development pathway for clinically trained investigators whose research requires direct involvement of human participants, providing dedicated time and mentorship to support a transition to research independence.
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