Opportunity Information: Apply for RFA RM 23 003
Pilot Projects Enhancing Utility and Usage of Common Fund Data Sets (R03 Clinical Trial Not Allowed) is an NIH discretionary grant opportunity (RFA-RM-23-003; CFDA 93.310) focused on getting more scientific value out of existing, widely available data sets produced by NIH Common Fund programs. Instead of funding new clinical trials or large-scale data generation, this FOA is designed to support small, targeted pilot projects that actively use selected Common Fund data resources in ways that demonstrate their real-world usefulness. The core idea is to help researchers and other eligible organizations show how these shared data sets can be leveraged to generate new hypotheses, uncover patterns, and catalyze discoveries that might not be apparent without cross-cutting analysis or novel re-use of existing data.
A key part of the program is practical impact: applicants are expected to do more than simply analyze a data set for a single narrow result. Projects should clearly enhance understanding of what the data can do, how it can be used effectively, and what kinds of scientific questions it is best suited to answer. This might involve developing or testing analysis approaches, integrating a Common Fund data set with complementary resources, exploring underused variables or modalities, validating analytical pipelines, or producing compelling proof-of-concept findings that illustrate the data set's value to a broader community. In addition to the research or analytic outcomes, awardees are explicitly asked to provide feedback on the utility of the Common Fund data resources, which signals that NIH is also using these pilot projects to learn what works well, what is confusing or limiting, and what improvements could make the data sets easier to access, interpret, or apply.
Eligibility is broad and includes many types of U.S.-based entities and organizations. Eligible applicants listed include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized governments; public housing authorities/Indian housing authorities; nonprofits (both 501(c)(3) and non-501(c)(3), other than institutions of higher education); for-profit organizations other than small businesses; and small businesses. The FOA also calls out additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal government agencies, regional organizations, and U.S. territories or possessions. At the same time, it draws a line on non-U.S. applicants: non-domestic (non-U.S.) entities (foreign organizations/institutions) are not eligible to apply, and non-domestic components of U.S. organizations are not eligible to apply. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed, meaning a U.S. applicant may include certain qualifying foreign elements in the project under NIH rules even though a standalone foreign institution cannot be the applicant organization.
Administratively, this is a grant mechanism under the NIH R03 activity, and the FOA is labeled "Clinical Trial Not Allowed," so proposed work must stay outside the definition of a clinical trial. The opportunity was created on 2022-11-25, with an original closing date of 2023-02-03. The posted source data does not specify an award ceiling or expected number of awards, so applicants typically would need to consult the full FOA text for budget limits, project duration, and any program-specific expectations about which Common Fund data sets are in scope, required deliverables, and how feedback to NIH should be structured or shared. Overall, the program is aimed at accelerating discovery by making sure high-value Common Fund data sets are not just available, but actively used, stress-tested, and improved through real pilot applications that also inform NIH about how these data resources can better serve the research community.Apply for RFA RM 23 003
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Pilot Projects Enhancing Utility and Usage of Common Fund Data Sets (R03 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310.
- This funding opportunity was created on 2022-11-25.
- Applicants must submit their applications by 2023-02-03. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Implementation Research on Noncommunicable Disease Risk Factors among Low- and Middle-Income Country and Tribal Populations Living in City Environments (R61/R33 Clinical Trial Required) Apply for PAR 23 043 Funding Number: PAR 23 043 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Research Networks to Promote Multidisciplinary Mechanistic Studies on Music-Based Interventions for Pain or Alzheimers Disease and Alzheimers Disease Related Dementias (AD/ADRD) (U24 Clinical Trial Optional) Apply for RFA AT 23 008 Funding Number: RFA AT 23 008 Agency: National Institutes of Health Category: Health Funding Amount: $300,000 |
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| NIH StrokeNet- Regional Coordinating Stroke Centers for year 2023 (U24 - Clinical Trials Not Allowed) Apply for RFA NS 23 010 Funding Number: RFA NS 23 010 Agency: National Institutes of Health Category: Health Funding Amount: $1,750,000 |
| NIH StrokeNet National Coordinating Center for year 2023 (U01 Clinical Trials Not Allowed) Apply for RFA NS 23 009 Funding Number: RFA NS 23 009 Agency: National Institutes of Health Category: Health Funding Amount: $1,750,000 |
| NIH StrokeNet National Data Management Center for year 2023 (U01 Clinical Trials Not Allowed) Apply for RFA NS 23 008 Funding Number: RFA NS 23 008 Agency: National Institutes of Health Category: Health Funding Amount: $1,000,000 |
| Research Networks to Promote Multidisciplinary Mechanistic Studies on Music-Based Interventions for Pain or Alzheimers Disease and Alzheimers Disease Related Dementias (AD/ADRD) (U24 Clinical Trial Optional) Apply for RFA AT 23 009 Funding Number: RFA AT 23 009 Agency: National Institutes of Health Category: Health Funding Amount: $300,000 |
| Limited Competition: Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) (P20 - Clinical Trial Optional) Apply for PAR 23 063 Funding Number: PAR 23 063 Agency: National Institutes of Health Category: Health Funding Amount: $1,500,000 |
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| Pilot Studies for the Spectrum of Alzheimers Disease/Alzheimers Disease-Related Dementias and Age-Related Cognitive Decline (R61 Clinical Trial Optional) Apply for PAR 23 083 Funding Number: PAR 23 083 Agency: National Institutes of Health Category: Health Funding Amount: $325,000 |
| Early and Late Stage Clinical Trials for the Spectrum of Alzheimers Disease/Alzheimers Related Dementias and Age-Related Cognitive Decline (R01 Clinical Trial Optional) Apply for PAR 23 081 Funding Number: PAR 23 081 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
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